Research

Cultural adaptation and evaluation of the effectiveness of evidence-based Cognitive Stimulation Therapy for people living with dementia: a randomized controlled trial.

Description

The objective of this study is to culturally adapt and evaluate the effectiveness of evidence-based Cognitive Stimulation Therapy (CST) among people living with mild to moderate dementia (PLMD) in Chile, both at the end of the intervention and at three months. Additionally, the study aims to identify predictors of its effect on various outcomes.

The research consists of two phases. The first involves the cultural adaptation of the CST manual through focus groups with professionals, PLMD, and caregivers, as well as a pilot study to assess its fidelity, acceptability, and feasibility. The second phase is a multicenter, pragmatic, randomized controlled trial to evaluate its effectiveness in real-world conditions.

The project will generate evidence on the short- and medium-term effects of CBT, as well as on factors influencing its outcomes, such as medication use and cognitive reserve. This will allow for the identification of profiles of individuals who could benefit most, thereby optimizing healthcare resources.

Finally, the study will include participants from different regions of the country and will use recommended methodologies, providing high-quality, context-specific evidence aligned with the National Dementia Plan and the comprehensive care model of GES 85.

The principal investigator of this Fondecyt Regular Project is Claudia Miranda. The co-investigators are Thamara Tapia and Andrea Slachevsky.